Title:
【発明の名称】融合されたベンゾ化合物
Document Type and Number:
Japanese Patent JPH08504410
Kind Code:
A
Abstract:
Fused benzo compounds of formula I are provided, wherein A is a 2 to 6 membered hydrocarbon spacer group, B is a polar divalent group selected from a group (a); U is C, N or CH; X is a divalent 3-4 membered chain optionally comprising one or more heteroatoms; R1 is an aliphatic hydrocarbon group, arylalkyl or diphenylalkyl; R2 and R3 are hydrogen or alkyl or together form an ethylene or propylene bridge; R4, R5 and R6 are hydrogen or substituents; R7 and R8 are hydrogen or substituents including -COOR9 and -CONR10R11; are 5-HT1A receptor ligands useful in the treatment of CNS disorders. Pharmaceutical compositions comprising the compounds and their use for the manufacture of a pharmaceutical preparation are also provided.\!
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Inventors:
Morzen Einel Kerr
Pellegold Jens Christian
Pedersen Henrik
Pellegold Jens Christian
Pedersen Henrik
Application Number:
JP51369194A
Publication Date:
May 14, 1996
Filing Date:
December 08, 1993
Export Citation:
Assignee:
Her Lundbeck Actieselskab
International Classes:
A61K31/335; A61K31/34; A61K31/343; A61K31/357; A61K31/36; A61K31/4427; A61K31/495; A61K31/496; A61P9/00; A61P9/10; A61P25/18; A61P25/20; A61P25/28; C07D233/32; C07D233/36; C07D307/79; C07D307/83; C07D317/46; C07D319/16; C07D319/18; C07D403/12; C07D405/02; C07D405/04; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D417/02; C07D417/12; C07D417/14; (IPC1-7): C07D233/32; C07D417/14; C07D409/14; C07D405/14; C07D405/04; C07D319/16; C07D317/46; C07D307/83; C07D307/79; A61K31/495; A61K31/36; A61K31/34; A61K31/335
Attorney, Agent or Firm:
Mitsuyoshi Esaki (3 outside)