Title:
【発明の名称】ヘリコバクター感染に対する免疫組成物、該組成物に用いられるポリペプチドおよび該ポリペプチドをコードする核酸配列
Document Type and Number:
Japanese Patent JPH08509873
Kind Code:
A
Abstract:
There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises:i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori, or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter felis urease, and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis, or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter pylori urease;ii) and/or, a heat shock protein (Hsp), or chaperonin, from Helicobacter, or a fragment of said protein.The preparation, by recombinant means, of such immunogenic compositions is also provided.
Inventors:
Rabinu, Agne
Sur baume, sebastian
Ferrero, Richard
Sur baume, sebastian
Ferrero, Richard
Application Number:
JP51417095A
Publication Date:
October 22, 1996
Filing Date:
November 19, 1993
Export Citation:
Assignee:
INSTITUT PASTEUR
Anstitu Nacional de la Sante et de la Rucherche Medical
Anstitu Nacional de la Sante et de la Rucherche Medical
International Classes:
C12N15/09; A61K38/00; A61K39/00; A61K39/02; A61K39/106; A61K39/39; A61K39/395; A61P1/04; A61P3/02; A61P31/04; A61P35/00; A61P37/02; C07H21/04; C07K14/195; C07K14/205; C07K16/12; C07K16/40; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/80; C12N15/31; C12P21/02; C12P21/08; C12Q1/68; G01N33/569; G01N33/574; C12R1/19; (IPC1-7): C12N15/09; C12Q1/68; C12P21/08; C12N9/80; C12N1/21; C07K16/40; C07K16/12; C07K14/195; A61K39/106
Attorney, Agent or Firm:
Takehiko Suzue (3 outside)