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Title:
コルチコトロピン放出因子阻害剤としてのイミダゾリル誘導体
Document Type and Number:
Japanese Patent JP2004531475
Kind Code:
A
Abstract:
The present invention relates to novel heterocyclic antagonists of Formula (I) and pharmaceutical compositions comprising said antagonists of the corticotropin releasing factor receptor ("CRF receptor") useful for the treatment of depression, anxiety, affective disorders, feeding disorders, post-traumatic stress disorder, headache, drug addiction, inflammatory disorders, drug or alcohol withdrawal symptoms and other conditions the treatment of which can be effected by the antagonism of the CRF-1 receptor.

Inventors:
Gene M. Devotive
Xiao Jun Han
Vivekananda M. Burdura
Dmitri Zhuev
Villeshwar Dasgupta
Jody A. Mitchin
Application Number:
JP2002559038A
Publication Date:
October 14, 2004
Filing Date:
January 11, 2002
Export Citation:
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Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
A61K31/41; A61K31/415; A61K31/4188; A61K31/437; A61K31/445; A61K31/454; A61K31/4545; A61K31/499; A61K31/519; A61K31/5377; A61K31/541; A61P1/00; A61P1/04; A61P1/12; A61P1/14; A61P3/04; A61P5/04; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P15/06; A61P15/08; A61P19/10; A61P25/00; A61P25/06; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/32; A61P25/36; A61P29/00; A61P37/04; A61K31/53; C07D235/02; C07D249/00; C07D401/00; C07D403/02; C07D471/14; C07D471/22; C07D487/00; C07D487/04; (IPC1-7): C07D471/14; A61K31/4188; A61K31/437; A61K31/454; A61K31/4545; A61K31/499; A61K31/519; A61K31/5377; A61K31/541; A61P1/00; A61P1/04; A61P1/12; A61P1/14; A61P3/04; A61P5/04; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P15/06; A61P15/08; A61P19/10; A61P25/00; A61P25/06; A61P25/08; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/32; A61P25/36; A61P29/00; A61P37/04; C07D471/22; C07D487/04
Attorney, Agent or Firm:
Mitsuo Tanaka
Kyousei Tamura
Nagatoshi Shinagawa