Title:
イミダゾピリジン化合物
Document Type and Number:
Japanese Patent JP2012510983
Kind Code:
A
Abstract:
The invention relates to compounds of formula (I): and their pharmaceutically acceptable salts and solvates, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.
Inventors:
Marianne, Nilsson
Haraldson, martin
Henrixon, Sofia
Emond Ricard
Savory, edward
Simpson, ian
Haraldson, martin
Henrixon, Sofia
Emond Ricard
Savory, edward
Simpson, ian
Application Number:
JP2011539096A
Publication Date:
May 17, 2012
Filing Date:
December 04, 2009
Export Citation:
Assignee:
PROXIMAGEN LTD.
International Classes:
C07D471/04; A61K31/424; A61K31/429; A61K31/437; A61K31/444; A61K31/4545; A61K31/496; A61K31/4985; A61K31/5025; A61K31/519; A61K31/5377; A61P1/00; A61P1/04; A61P1/12; A61P1/16; A61P3/10; A61P7/04; A61P9/00; A61P9/04; A61P9/08; A61P9/10; A61P11/00; A61P11/06; A61P11/08; A61P11/14; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P25/00; A61P25/28; A61P29/00; A61P31/04; A61P37/02; A61P37/08; A61P43/00; C07D487/04; C07D498/04; C07D513/04
Domestic Patent References:
| JP2008542323A | 2008-11-27 | |||
| JP2008519805A | 2008-06-12 | |||
| JP2004506633A | 2004-03-04 | |||
| JPH03181419A | 1991-08-07 | |||
| JPS62169784A | 1987-07-25 | |||
| JPS6147485A | 1986-03-07 |
Foreign References:
| WO2007069565A1 | 2007-06-21 | |||
| WO2007019344A1 | 2007-02-15 |
Other References:
GIUSEPPE TRAPANI ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. 40, no. 19, JPN6014002132, 1997, pages 3109 - 3118, ISSN: 0002728227
GERARD GRASSY ET AL., CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, JPN6014002136, 1993, pages 71 - 84, ISSN: 0002728228
ALDO ANDREANI ET AL., JOURNAL OF HETEROCYCLIC CHEMISTRY, JPN6014002138, 1989, pages 525 - 529, ISSN: 0002728229
ALDO ANDREANI ET AL., ARCHIV DER PHARMAZIE, vol. 315, JPN6014002141, 1982, pages 451 - 456, ISSN: 0002728230
LUIGI ALMIRANTE ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. 13, no. 6, JPN6014002143, 1970, pages 1048 - 1051, ISSN: 0002728231
GUNDURAO KOLAVI ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, JPN6014002145, 2006, pages 3069 - 3080, ISSN: 0002728232
SYLVIE MAVEL ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, JPN6014002129, 2002, pages 941 - 946, ISSN: 0002728226
GERARD GRASSY ET AL., CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, JPN6014002136, 1993, pages 71 - 84, ISSN: 0002728228
ALDO ANDREANI ET AL., JOURNAL OF HETEROCYCLIC CHEMISTRY, JPN6014002138, 1989, pages 525 - 529, ISSN: 0002728229
ALDO ANDREANI ET AL., ARCHIV DER PHARMAZIE, vol. 315, JPN6014002141, 1982, pages 451 - 456, ISSN: 0002728230
LUIGI ALMIRANTE ET AL., JOURNAL OF MEDICINAL CHEMISTRY, vol. 13, no. 6, JPN6014002143, 1970, pages 1048 - 1051, ISSN: 0002728231
GUNDURAO KOLAVI ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, JPN6014002145, 2006, pages 3069 - 3080, ISSN: 0002728232
SYLVIE MAVEL ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, JPN6014002129, 2002, pages 941 - 946, ISSN: 0002728226
Attorney, Agent or Firm:
Shintaro Nogawa
Masanori Akiyama
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto
Masanori Akiyama
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto