Title:
Ｃ型レクチンを介する免疫
Document Type and Number:
Japanese Patent JP5577246
Kind Code:
B2
Abstract:
The invention relates to the regulation of the immune system, and in particular to the finding that the CLEC9a molecule is a marker for dendritic cells which are capable of cross-presenting extracellular antigens via the MHC class I pathway. This makes them particularly suitable for generation of cytotoxic T lymphocyte responses. Materials and methods are provided both for the induction of immune responses against target antigens, and for the inhibition or suppression of undesirable immune responses in which these cells are involved.
Inventors:
David Sancho * Madrid
Oliver Shultz
Neal Charles Rogers
カエタノ lease E Sosa
Daniel Pennington
Oliver Pierre Geoffray
Oliver Shultz
Neal Charles Rogers
カエタノ lease E Sosa
Daniel Pennington
Oliver Pierre Geoffray
Application Number:
JP2010516587A
Publication Date:
August 20, 2014
Filing Date:
July 21, 2008
Export Citation:
Assignee:
Cancer research technology Limited CANCER RESEARCH TECHNOLOGY LIMITED
International Classes:
A61K39/00; A61K39/39; A61K39/395; A61P31/12; A61P35/00; A61P37/04; C12N5/00; C12N5/0783; C12N5/0784
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Jitsuhiro