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Title:
IMMUNOASSAY OF S-ADENOSYLMETHIONINE USING ANALOGS THEREOF AND PERSONALIZED THERAPEUTICS
Document Type and Number:
Japanese Patent JP2022119827
Kind Code:
A
Abstract:
To provide a method of detecting the presence or absence of disease accompanied by a deficient level of S-adenosylmethionine in a patient.SOLUTION: A method provided herein comprises: identifying a patient suspected of having such disease or at risk of having the disease; obtaining a biological sample from said patient; determining a level of S-adenosylmethionine in the biological sample using an antibody derived from a hapten analog of S-adenosylmethionine; and correlating the level of S-adenosylmethionine with presence or absence of the disease. The present invention also provides methods of measuring SAH used to determine a methylation index (ratio of SAM/SAH) indicative of a health status of an individual.SELECTED DRAWING: None

Inventors:
HAO XIUJUAN
ISAAC A ANGRES
Application Number:
JP2022080393A
Publication Date:
August 17, 2022
Filing Date:
May 16, 2022
Export Citation:
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Assignee:
HUNAN SKYWORLD BIOTECHNOLOGIES CO
International Classes:
G01N33/574; A61K31/7076; A61K45/00; A61P25/00; A61P35/00; A61P35/02; C07H19/167
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes