Title:
免疫原およびそのスクリーニング方法
Document Type and Number:
Japanese Patent JP2013525271
Kind Code:
A
Abstract:
The present application is generally directed to methods for identifying immunogens from organisms and pathogens, and in particular for identifying immunogens which when administered as vaccines elicit a cellular and/or humoral immune response. The present application is also directed to pneumococcal T-cell immunogens, and vaccine compositions comprising one or a combination of pneumococcal immunogens and methods for treating or preventing pneumococcal infections using the vaccines thereof. The present invention also encompasses use of the pneumococcal immunogens for diagnostic purposes to identify a subject with a pneumococcal infection.
Inventors:
Murray Richard
Ruinjae
Mofit Christine Elle.
Ruinjae
Mofit Christine Elle.
Application Number:
JP2013500099A
Publication Date:
June 20, 2013
Filing Date:
March 11, 2011
Export Citation:
Assignee:
Children's Medical Center Corporation
International Classes:
A61K39/00; A61K39/002; A61K39/02; A61K39/09; A61K39/12; A61K39/39; A61P31/00; A61P31/10; A61P31/12; A61P33/00; C07K4/02; C07K4/04; C07K4/06; C07K4/12; C12N15/09; C12P1/02; C12P1/04; C12P7/64; C12P19/00; C12P21/00
Domestic Patent References:
| JP2003515341A | 2003-05-07 | |||
| JP2007525157A | 2007-09-06 | |||
| JP2003515341A | 2003-05-07 | |||
| JP2007525157A | 2007-09-06 |
Foreign References:
| WO1990011087A1 | 1990-10-04 | |||
| WO1990011087A1 | 1990-10-04 |
Other References:
JPN6015020928; Ｉｎｆｅｃｔ． Ｉｍｍｕｎ．， ２００１， ６９（８）， ｐｐ．４８７０-４８７３
JPN6015020926; Ｊ． Ａｐｐｌ． Ｂａｃｔｅｒｉｏｌ．， １９９０， ６９（５）， ｐｐ．６７６-６８５
JPN6015020927; Ｉｎｆｅｃｔ． Ｉｍｍｕｎ．， ２００７， ７５（１１）， ｐｐ．５４６０-５４６４
JPN7015001427; ＦＥＭＳ Ｍｉｃｒｏｂｉｏｌ． Ｌｅｔｔ．， ２００６， ２６２（１）， ｐｐ．１４-２１
JPN6015020926; Ｊ． Ａｐｐｌ． Ｂａｃｔｅｒｉｏｌ．， １９９０， ６９（５）， ｐｐ．６７６-６８５
JPN6015020927; Ｉｎｆｅｃｔ． Ｉｍｍｕｎ．， ２００７， ７５（１１）， ｐｐ．５４６０-５４６４
JPN7015001427; ＦＥＭＳ Ｍｉｃｒｏｂｉｏｌ． Ｌｅｔｔ．， ２００６， ２６２（１）， ｐｐ．１４-２１
JPN6015020926; Ｊ． Ａｐｐｌ． Ｂａｃｔｅｒｉｏｌ．， １９９０， ６９（５）， ｐｐ．６７６-６８５
JPN6015020927; Ｉｎｆｅｃｔ． Ｉｍｍｕｎ．， ２００７， ７５（１１）， ｐｐ．５４６０-５４６４
JPN7015001427; ＦＥＭＳ Ｍｉｃｒｏｂｉｏｌ． Ｌｅｔｔ．， ２００６， ２６２（１）， ｐｐ．１４-２１
JPN6015020926; Ｊ． Ａｐｐｌ． Ｂａｃｔｅｒｉｏｌ．， １９９０， ６９（５）， ｐｐ．６７６-６８５
JPN6015020927; Ｉｎｆｅｃｔ． Ｉｍｍｕｎ．， ２００７， ７５（１１）， ｐｐ．５４６０-５４６４
JPN7015001427; ＦＥＭＳ Ｍｉｃｒｏｂｉｏｌ． Ｌｅｔｔ．， ２００６， ２６２（１）， ｐｐ．１４-２１
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto