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Title:
免疫グロブリン精製方法及び免疫グロブリン精製装置、並びに免疫グロブリン製造方法及び免疫グロブリン製造装置
Document Type and Number:
Japanese Patent JP7090300
Kind Code:
B2
Abstract:
To provide an immunoglobulin purification method which achieves a high immunoglobulin recovery percentage without causing loss of the antibody nature of an immunoglobulin. The immunoglobulin purification method includes an adsorption step and a desorption step. The adsorption step involves adsorption of an immunoglobulin onto porous zirconia particles in a neutral buffer. The desorption step involves desorption of the immunoglobulin adsorbed on the porous zirconia particles from the porous zirconia particles by means of a neutral desorption liquid.

Inventors:
Katu Kataya
Nagahisa Hisae
Shinjiro Kasahara
Yuki Hirobe
Atsushi Otsuka
Application Number:
JP2020568123A
Publication Date:
June 24, 2022
Filing Date:
January 17, 2020
Export Citation:
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Assignee:
Nippon Special Ceramics Co., Ltd.
National Institute of Advanced Industrial Science and Technology
International Classes:
C07K1/22; B01J20/06; C07K16/00
Domestic Patent References:
JP2017047365A
Foreign References:
US20040007530
Other References:
Journal of Chromatography A, 1999,Vol.831, pp.63-72
Protein Expression and Purification, 2004, Vol.37, pp.399-408
Journal of Chromatography A, 2000, Vol.890, pp.15-23
Attorney, Agent or Firm:
Patent Attorney Corporation Grund Patent Office