Title:
IMMUNOLOGICALLY ACTIVE DIPEPTIDYL-5-0, 6-0-ACYL-2-AMINO-2-DEOXY-D-GLUCOFURANOSE DERIVATIVE AND MANUFACTURE
Document Type and Number:
Japanese Patent JPS56169697
Kind Code:
A
Abstract:
Immunologically active compounds of the formula: (I.) hydrogen; C1-30 alkyl; C2-30 alkenyl; C1-30 alkoxy; phenyl; C1-20 alkylsulfonyl; or cholesteryl; and R4 may additionally be hydrogen; R5 is hydrogen; or R5-R6 together is -CH2-CH2-CH2; R6 is hydrogen; C1-7 alkyl; hydroxymethyl; mercapto-methyl; benzyl; or substituted benzyl; R7 and R8 may be the same or different and are each independently COOR or CONR'R'', where R is hydrogen or C1-7 alkyl, and R' and R'' are each independently hydrogen or C1-3 alkyl; when R2 is C1-10 alkyl, the stereochemistry at asymmetric center I can be either D or L; when R6 is not hydrogen, the stereochemistry at asymmetric center Ii is L; the stereochemistry at asymmetric center III is D.
Inventors:
FUIRITSUPU ERU DEYURETSUTO
Application Number:
JP6707581A
Publication Date:
December 26, 1981
Filing Date:
May 06, 1981
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
A61K31/70; A61K39/39; C07H15/04; C07J17/00; C07K9/00; (IPC1-7): A61K39/39; C07H15/04; C07J17/00