To provide methods and products for inducing IL-2 secretion, inducing IL-10 secretion, activating T cells, suppressing IgG antibody response to specific antigen, promoting allograft survival, reducing adhesion formation after surgical operation, and protecting against abscess formation associated with surgery, trauma or diseases that predispose the host to abscess formation.
The method includes locally administrating a polymer having at least two repeating charge motifs separated by at least a certain minimum distance, preferably a zwitterionic non-polysaccharide polymer. The repeating charge motif includes a positively charged free amino moiety and a negative charge, and the positively charged free amino moieties of at least two repeating charge motifs are preferably separated by a distance of at least 32 .
KASPER DENNIS L
ONDERDONK ANDREW B
WANG YING