Title:
免疫調節剤
Document Type and Number:
Japanese Patent JP6976263
Kind Code:
B2
Abstract:
The present disclosure provides novel macrocyclic compounds which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
Inventors:
Martin Patrick Allen
Eric P. Gillis
David Earl Langley
Michael Matthew Miller
Eric Maru
Lee Chiang Soon
Cap-Sung Yeun
Catherine A. Grant-Young
Nicholas A. Meanwell
Paul Michael Scola
Eric P. Gillis
David Earl Langley
Michael Matthew Miller
Eric Maru
Lee Chiang Soon
Cap-Sung Yeun
Catherine A. Grant-Young
Nicholas A. Meanwell
Paul Michael Scola
Application Number:
JP2018546499A
Publication Date:
December 08, 2021
Filing Date:
March 02, 2017
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07K7/56; A61K38/10; A61K45/00; A61P31/12; A61P35/00; A61P37/04; A61P43/00; C07K7/08
Domestic Patent References:
| JP2015512910A |
Foreign References:
| WO2014151634A1 | ||||
| WO2015044900A1 |
Other References:
ChemMedChem,2016年,Vol.11,p.787-794,(2015年11月13日オンライン掲載), DOI:10.1002/cmdc.201500450
Journal of the American Chemical Society,2013年,Vol.135, No.32,p.11990-11995
Molecular Medicine Reports,2012年,Vol.6,p.553-557
Journal of the American Chemical Society,2013年,Vol.135, No.32,p.11990-11995
Molecular Medicine Reports,2012年,Vol.6,p.553-557
Attorney, Agent or Firm:
Norihito Yamao
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro
Nagatoshi Shinagawa
Kure Hidenori
Kamahira Futami
Mizuhara Masahiro
Previous Patent: Electric hub for furniture assembly
Next Patent: In-line processing system and method of yarn used with yarn consuming equipment
Next Patent: In-line processing system and method of yarn used with yarn consuming equipment