Title:
ポリペプチド製造用の改良されたα因子シグナル・ペプチド
Document Type and Number:
Japanese Patent JP2010507381
Kind Code:
A
Abstract:
The present invention relates to a method for producing a polypeptide comprising using a variant alpha factor signal peptide having a substitution in position 9 resulting in a substitution of an A to either T, S, H, I, F, E, or G. The invention further relate to nucleic acid constructs comprising a first nucleotide sequence encoding the variant signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising said nuclei acid construct.
Inventors:
Draboau, Henriette
Application Number:
JP2009533810A
Publication Date:
March 11, 2010
Filing Date:
October 23, 2007
Export Citation:
Assignee:
Novozymes actiesel scab
International Classes:
C12N15/09; C07K14/395; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Kazuhiro Nakamura
Masaru Nakajima