Title:
医薬製剤用ＰＩ３Ｋデルタ選択的抑制剤の改良形態
Document Type and Number:
Japanese Patent JP6987501
Kind Code:
B2
Abstract:
The divisional application relates to a pharmaceutical composition comprising a p-toluenesulfonic acid salt (PTSA) of the selective PI3K delta inhibitor (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one (TGR-1202) and a solubilizer, and to the pharmaceutical composition for use in the treatment of a PI3K kinase mediated disease or disorder such as cancer.
Inventors:
Swallow, Kumar, Venkata, Satya, Vakalanka
Application Number:
JP2016569636A
Publication Date:
January 05, 2022
Filing Date:
May 26, 2015
Export Citation:
Assignee:
Reisen Pharmaceuticals S.A.R.
International Classes:
C07D487/04; A61K31/519; A61K45/00; A61P1/00; A61P1/02; A61P1/04; A61P1/16; A61P3/00; A61P3/06; A61P5/14; A61P7/00; A61P7/06; A61P9/08; A61P9/10; A61P11/00; A61P11/02; A61P13/00; A61P13/10; A61P13/12; A61P15/00; A61P15/02; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P21/04; A61P25/16; A61P25/18; A61P27/02; A61P29/00; A61P31/06; A61P31/08; A61P31/18; A61P31/22; A61P35/00; A61P37/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00
Foreign References:
| WO2014006572A1 |
Other References:
平山令明編著、有機化合物結晶作製ハンドブック -原理とノウハウ-、丸善株式会社、平成20年7月25日発行、pp.17-23、37-40、45-51、57-65
Pharmaceutical Research、(1995)、Vol.12、No.7、pp.945-954
International Scholarly Research Network ISRN Pharmaceutics、(2012)、Vol.2012、pp.1-10
浅原照三 外4名編、溶剤ハンドブック、株式会社講談社、1985年9月1日 第6刷発行、pp.47~51
Pharmaceutical Research、(1995)、Vol.12、No.7、pp.945-954
International Scholarly Research Network ISRN Pharmaceutics、(2012)、Vol.2012、pp.1-10
浅原照三 外4名編、溶剤ハンドブック、株式会社講談社、1985年9月1日 第6刷発行、pp.47~51
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe