統合失調症の記憶・学習機能障害治療薬のinvivoスクリーニング方法

Title:

統合失調症の記憶・学習機能障害治療薬のinvivoスクリーニング方法

Document Type and Number:

Japanese Patent JP4847320

Kind Code:

B2

Abstract:

A method of evaluating memory/ learning functions with the use of a model with glutamic acid N-methyl-D-aspartate (NMDA) type receptor hypofunction as an animal model for schizophrenia and with the use of reference memory task, wherein there has been found concrete means for detecting any differences in activity between typical anti-psycliosis drugs and atypical anti-psychosis drugs is found. An in vivo animal model for screening of a therapeutic agent for improving cognitive dysfunction by schizophrenia is provided.

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Inventors:

Takeo Ishiyama

Application Number:

JP2006510283A

Publication Date:

December 28, 2011

Filing Date:

February 16, 2005

Export Citation:

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Assignee:

Sumitomo Dainippon Pharma Co., Ltd.

International Classes:

A61K31/496; A61K31/445; A61K31/551; A61K31/554; A61K45/00; A61P25/28; A61P43/00; C07D211/32; C07D243/10; C07D281/14; C07D417/12; G01N33/15; G01N33/50

Foreign References:

WO1996014297A1

1996-05-17

Attorney, Agent or Firm:

Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Yobe

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