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Title:
インデニル化合物、医薬組成物、およびその医学的使用
Document Type and Number:
Japanese Patent JP6698089
Kind Code:
B2
Abstract:
Disclosed are compounds, for example, compounds of formula I,wherein R, R0, R1-R8, n, X, Y, Y', and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.

Inventors:
Piazza, Gary A.
Chain, sea
Keaton, Adam Bee.
Boyd, Michael Earl.
Application Number:
JP2017533501A
Publication Date:
May 27, 2020
Filing Date:
December 16, 2015
Export Citation:
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Assignee:
AD Pharmaceuticals, LRC
International Classes:
C07C237/20; A61K31/165; A61K31/216; A61K31/341; A61K31/40; A61K31/4406; A61K31/4409; A61K31/443; A61K31/445; A61K31/495; A61K31/496; A61K31/505; A61K31/506; A61K31/661; A61K31/665; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07C259/06; C07D207/14; C07D207/335; C07D211/56; C07D213/40; C07D213/56; C07D239/42; C07D295/192; C07D307/52; C07D307/54; C07D401/12; C07D405/12; C07F9/12; C07F9/655
Domestic Patent References:
JP2007534702A
JP2000514417A
JP2009522364A
JP2004510762A
JP2002508358A
Foreign References:
DE10163426A1
WO2014047592A1
Other References:
European Journal of Medicinal Chemistry,2012年,56,pp.17-29
Angew. Chem. Int. Ed.,2004年,43,pp.450-454
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto