Title:
【発明の名称】新規ビタミンD類似体
Document Type and Number:
Japanese Patent JP2807083
Kind Code:
B2
Abstract:
The present invention relates to compounds of formula (I), in which formula R stands for an alkyl group containing from 7 to 12 carbon atoms optionally substituted with a hydroxy group; and derivatives of the compounds of formula (I) in which one or more hydroxy groups have been transformed into -O-acyl or -O-glycosyl or phosphate ester groups, such masked groups being hydrolyzable in vivo, in pure form or in mixtures. The present compounds find use in both the human and veterinary practice in the treatment and prophylaxis of autoimmune diseases, including diabetes mellitus, hypertension, inflammatory diseases such as rheumatoid arthritis and asthma as well as diseases characterized by abnormal cell differentiation and/or cell proliferation, and/or imbalance in the immune system.
Inventors:
Calvary, Martin John
Hansen, Kai
Binerup, lycee
Hansen, Kai
Binerup, lycee
Application Number:
JP50412690A
Publication Date:
September 30, 1998
Filing Date:
February 13, 1990
Export Citation:
Assignee:
Leo Pharmaceutical Products Limited A/S
International Classes:
A61P3/08; A61P9/12; A61P11/00; A61K31/59; A61P35/00; A61P37/00; C07C401/00; (IPC1-7): C07C401/00; A61K31/59
Other References:
【文献】欧州公開184112(EP,A2)
【文献】Chem,Pharm.Bull.,Vol.34,No.10 (1986) P.4410-P.4413
【文献】Chem,Pharm.Bull.,Vol.34,No.10 (1986) P.4410-P.4413
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)