Title:
バイオフィルム生物の阻害
Document Type and Number:
Japanese Patent JP5727994
Kind Code:
B2
Abstract:
The present invention relates to a product comprising at least two antibiofilm agents wherein at least one of the antibiofilm agents is an antimicrobial peptide. The second antibiofilm agent is cysteamine. There is also provided the use of the product in the treatment of a microbial infection.
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Inventors:
O'Neill, Deborah
Martha, Delhi
Charlier, Cedric
Martha, Delhi
Charlier, Cedric
Application Number:
JP2012502770A
Publication Date:
June 03, 2015
Filing Date:
March 31, 2010
Export Citation:
Assignee:
NOVABIOTICS LIMITED
International Classes:
A61K31/131; A61K31/198; A61K38/00; A61K38/08; A61L15/44; A61L27/00; A61L29/00; A61L31/00; A61P1/02; A61P13/02; A61P17/00; A61P31/04
Domestic Patent References:
| JP2005539056A |
Foreign References:
| WO2008093058A1 | ||||
| WO2007050565A1 |
Other References:
Oosterhof,J.J. et al.,The influence of antimicrobial peptides and mucolytics on the integrity of biofilms consisting of bacteria and yeasts as affecting voice prosthetic air flow resistances,Biofouling,2003年,Vol.19,No.6,p.347-353
Jayaraman,A. et al.,Inhibiting sulfate-reducing bacteria in biofilms by expressing the antimicrobial peptides indolicidin and bactenecin,Journal of Industrial Microbiology & Biotechnology,1999年,Vol.22,p.167-175
Beckloff N.et al.,Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens,Antimicrob. Agents Chemother.,2007年,Vol.51,No.11,p.4125-4132
Jayaraman,A. et al.,Inhibiting sulfate-reducing bacteria in biofilms by expressing the antimicrobial peptides indolicidin and bactenecin,Journal of Industrial Microbiology & Biotechnology,1999年,Vol.22,p.167-175
Beckloff N.et al.,Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens,Antimicrob. Agents Chemother.,2007年,Vol.51,No.11,p.4125-4132
Attorney, Agent or Firm:
Naoto Uchida