Title:
INHIBITOR OF INTERLEUKIN-1-CONVERTING ENZYME
Document Type and Number:
Japanese Patent JP2008101008
Kind Code:
A
Abstract:
To provide a medicine for preventing and treating chronic and acute diseases mediated by IL-1, diseases mediated by apoptosis, and inflammatory diseases, autoimmune diseases, osteoclastic diseases, proliferative disorders, infectious diseses, degenerative diseases or necrotic diseases.
This inhibitor of IL-1-converting enzyme is a compound expressed by formula [wherein, (n) is 1 to 2; and R11s are each formula (a) or (b)].
Inventors:
BEMIS GUY W
DUFFY JOHN P
FRIDMAN WOLF HERMAN
GOLEC JULIAN M C
LIVINGSTON DAVID J
MULLICAN MICHAEL D
MURCKO MARK A
ZELLE ROBERT E
DUFFY JOHN P
FRIDMAN WOLF HERMAN
GOLEC JULIAN M C
LIVINGSTON DAVID J
MULLICAN MICHAEL D
MURCKO MARK A
ZELLE ROBERT E
Application Number:
JP2007292640A
Publication Date:
May 01, 2008
Filing Date:
November 09, 2007
Export Citation:
Assignee:
VERTEX PHARMACEUT INC
International Classes:
A61K38/00; A61K38/55; C07K5/062; A61P1/00; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P5/14; A61P7/00; A61P7/06; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P17/14; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P31/00; A61P31/04; A61P31/18; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P43/00; C07K5/00; C07K5/02; C07K5/08; C07K5/083
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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