Title:
プレニルトランスフェラーゼの阻害剤
Document Type and Number:
Japanese Patent JP4138826
Kind Code:
B2
Abstract:
Compounds which inhibit prenyl transferases, particularly farnysyltransferase and geranylgeranyl transferase I, processes for preparing the compounds, pharmaceutical compositions containing the compounds, and methods of use.
Inventors:
Cebuti, Seid
Andrew, Hamilton
Andrew, Hamilton
Application Number:
JP2006209503A
Publication Date:
August 27, 2008
Filing Date:
August 01, 2006
Export Citation:
Assignee:
UNIVERSITY OF PITTSBURGH
International Classes:
C07C323/59; C07D277/20; A61K31/195; A61K31/215; A61K31/42; A61K31/421; A61K31/425; A61K31/426; A61K31/44; A61K38/00; A61K38/55; A61P35/00; A61P43/00; C07C323/25; C07C323/60; C07C329/06; C07D207/34; C07D213/56; C07D215/38; C07D217/22; C07D257/04; C07D263/48; C07D277/38; C07D277/40; C07D307/66; C07K5/103; C07K5/107
Domestic Patent References:
| JP10501259A |
Foreign References:
| WO1994014817A1 |
Other References:
The Journal of Biological Chemistry,(1994),269(17),p12410-12413
Bioorganic& Medicinal Chemistry Letters,(1994),4(21),p2579-2584
Bioorganic& Medicinal Chemistry Letters,(1994),4(23),p2775-2780
J.Clin.Chem.Clin.Biochem.,(1981),19,p145-154
Acta biol.med.germ.,(1978),37(8),p1205-1214
Bioorganic& Medicinal Chemistry Letters,(1994),4(21),p2579-2584
Bioorganic& Medicinal Chemistry Letters,(1994),4(23),p2775-2780
J.Clin.Chem.Clin.Biochem.,(1981),19,p145-154
Acta biol.med.germ.,(1978),37(8),p1205-1214
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda