Title:
ウンデカプレニルピロホスフェートシンターゼの阻害剤
Document Type and Number:
Japanese Patent JP2009544732
Kind Code:
A
Abstract:
The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as bacterial infection.
Inventors:
Timothy Bryan Harley
Li Kwanho
Stephan Peukert
Sompong Wattanashin
Li Kwanho
Stephan Peukert
Sompong Wattanashin
Application Number:
JP2009521974A
Publication Date:
December 17, 2009
Filing Date:
July 25, 2007
Export Citation:
Assignee:
NOVARTIS AG
International Classes:
A61K45/00; A61K31/4025; A61K31/435; A61K31/4355; A61K31/4365; A61K31/437; A61K31/444; A61K31/4545; A61K31/4704; A61K31/4709; A61K31/496; A61K31/5377; A61K31/541; A61P31/04; A61P43/00; C07D215/56; C07D221/04; C07D311/74; C07D401/06; C07D401/12; C07D413/12; C07D471/04; C07D491/048; C07D495/04
Domestic Patent References:
| JP2002527049A | 2002-08-27 | |||
| JPS5018480A | 1975-02-26 | |||
| JP2003012667A | 2003-01-15 | |||
| JPH07509488A | 1995-10-19 |
Foreign References:
| WO2006076009A2 | 2006-07-20 |
Other References:
JPN6012024242; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１２, 2004, ｐ．９３５-９４７
JPN5009010816; ＩＣＨＩＫＡＷＡ: ＣＨＥＭＩＣＡＬ ＡＮＤ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ Ｖ１７ Ｎ１１, 19691125, Ｐ２３８４-２３８８
JPN6012024243; Ｐｈａｒｍａｚｉｅ Ｖｏｌ．３９， Ｎｏ．２, 1984, ｐ．８６-９１
JPN5009010816; ＩＣＨＩＫＡＷＡ: ＣＨＥＭＩＣＡＬ ＡＮＤ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ Ｖ１７ Ｎ１１, 19691125, Ｐ２３８４-２３８８
JPN6012024243; Ｐｈａｒｍａｚｉｅ Ｖｏｌ．３９， Ｎｏ．２, 1984, ｐ．８６-９１
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa