Title:
ＡＰＯＬ１の阻害剤及びその使用
Document Type and Number:
Japanese Patent JP2023529216
Kind Code:
A
Abstract:
本開示は、式Ｉの化合物、それらの化合物の重水素化誘導体、並びにそれらの化合物及び誘導体の薬学的に許容される塩、同化合物を含む組成物、及びＡＰＯＬ１媒介性腎疾患の治療における使用を含む、同化合物を使用する方法を提供する。TIFF2023529216000353.tif4194
Inventors:
Tsao, Jinlong
Cam, John H.
Dakin, Leslie A.
Dennis, Francois
Dorsch, Warren A.
Fotia, Ann
Hamel, Martin
Kluger, Elaine Bee.
Redford, Brian
Maltheis, François
Nantha Kumar, Sgantinies.
Nicholas, Olivier
Sayeg, Camille Yee.
Center, Timothy Jay.
Wang, Tian Shen
Cam, John H.
Dakin, Leslie A.
Dennis, Francois
Dorsch, Warren A.
Fotia, Ann
Hamel, Martin
Kluger, Elaine Bee.
Redford, Brian
Maltheis, François
Nantha Kumar, Sgantinies.
Nicholas, Olivier
Sayeg, Camille Yee.
Center, Timothy Jay.
Wang, Tian Shen
Application Number:
JP2022575988A
Publication Date:
July 07, 2023
Filing Date:
June 11, 2021
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D209/12; A61K31/404; A61K31/4155; A61K31/4178; A61K31/4192; A61K31/422; A61K31/4245; A61K31/427; A61K31/4439; A61K31/454; A61K31/497; A61K31/501; A61K31/506; A61K31/513; A61P3/10; A61P7/00; A61P13/12; A61P43/00; C07D209/14; C07D209/18; C07D209/30; C07D209/40; C07D401/06; C07D401/12; C07D403/06; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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