Title:
INHIBITORS OF GLUCOCORTICOID RECEPTOR
Document Type and Number:
Japanese Patent JP2021046409
Kind Code:
A
Abstract:
To provide novel compounds for treating or preventing cancer.SOLUTION: Provided herein are substituted steroidal derivative compounds having the structure in the figure, and pharmaceutical compositions comprising the compounds. The subject compounds and compositions are useful as inhibitors of glucocorticoid receptors (GRs).SELECTED DRAWING: None
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Inventors:
SUN DAQING
LAWRENCE R MCGEE
DU XIAOHUI
ZHU LIUSHENG
YAN XUELEI
REW YOSUP
JOHN EKSTEROWICZ
JULIO C MEDINA
VALERIA R FANTIN
ZHOU HAIYING
MINNA DELARAE BALBAS
LAWRENCE R MCGEE
DU XIAOHUI
ZHU LIUSHENG
YAN XUELEI
REW YOSUP
JOHN EKSTEROWICZ
JULIO C MEDINA
VALERIA R FANTIN
ZHOU HAIYING
MINNA DELARAE BALBAS
Application Number:
JP2020191820A
Publication Date:
March 25, 2021
Filing Date:
November 18, 2020
Export Citation:
Assignee:
ORIC PHARMACEUTICALS INC
International Classes:
C07J1/00; A61K31/282; A61K31/337; A61K31/4745; A61K31/567; A61K31/569; A61K31/58; A61K31/704; A61K31/7068; A61K33/243; A61K33/26; A61K33/30; A61K33/32; A61K33/34; A61K45/00; A61P5/46; A61P11/00; A61P13/08; A61P15/00; A61P35/00; A61P43/00; C07J17/00; C07J41/00
Domestic Patent References:
| JP6995757B2 | 2022-01-17 |
Foreign References:
| US5843933A | 1998-12-01 | |||
| US5728689A | 1998-03-17 |
Other References:
STEROIDS, vol. ９２, JPN6021000842, 2014, pages 45 - 55, ISSN: 0004841958
Attorney, Agent or Firm:
Kazuhiro Kiyohara