Title:
ヒストン脱アセチル化酵素の阻害剤
Document Type and Number:
Japanese Patent JP5290065
Kind Code:
B2
Abstract:
The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
Inventors:
Derrome daniel
Ruel Les Jeans
Lavoyer Rico
Tibort curl
Abu-Karyl Erie
Ruel Les Jeans
Lavoyer Rico
Tibort curl
Abu-Karyl Erie
Application Number:
JP2009147470A
Publication Date:
September 18, 2013
Filing Date:
June 22, 2009
Export Citation:
Assignee:
Methyl Gene Incorporated
International Classes:
C07C259/06; C12N9/99; A61K31/10; A61K31/16; A61K31/165; A61K31/166; A61K31/17; A61K31/18; A61K31/341; A61K31/343; A61K31/381; A61K31/433; A61K31/44; A61K31/4402; A61K31/4406; A61K31/47; A61K31/711; A61K48/00; A61P9/10; A61P17/06; A61P31/00; A61P31/10; A61P35/00; A61P43/00; C07C259/10; C07C275/42; C07C311/13; C07C311/21; C07C311/29; C07C311/44; C07C317/24; C07C317/44; C07D213/71; C07D213/76; C07D215/36; C07D285/135; C07D307/46; C07D307/54; C07D307/68; C07D307/91; C07D333/34; C07D333/38; C07D333/62; C07D285/12
Domestic Patent References:
| JP10182583A | ||||
| JP4217950A | ||||
| JP11302173A |
Foreign References:
| WO1998055449A1 |
Other References:
Zara-Kaczian, Erzsebet 他,Synthesis of 1-aryl-1,4-dihydro-2-carbamoyl-3(2H)-isoquinolinones and their reaction with amines. A new method for the preparation of 2-{[α-(N'-phenylureido)]benzyl}phenylacetamides,Acta Chimica Academiae Scientiarum Hungaricae,1979年,100(1-4),37-52
MANFRED JUNG,J MED CHEM,1999年11月 4日,V42 N22,P4669-4679
Oncogene,Apr. 15 1999, 18, p.2461-2470
MANFRED JUNG,J MED CHEM,1999年11月 4日,V42 N22,P4669-4679
Oncogene,Apr. 15 1999, 18, p.2461-2470
Attorney, Agent or Firm:
Kiyoji Kuzuwa