Title:
ミトコンドリアの電子伝達系の複合体IIIの活性の阻害剤、及び疾患を治療するためのその使用
Document Type and Number:
Japanese Patent JP2014503504
Kind Code:
A
Abstract:
The present invention relates to compounds which are inhibitors of the activity of Complex III of the mitochondrial electron transport chain and pharmaceutical compositions comprising said compounds alone or in combination with other active agents. The present invention further relates to use of the compounds of the invention as medicaments or as agrochemicals where their properties as inhibitors of the mitochondrial respiration is of benefit. More particularly the present invention relates to the use of the compounds of the invention in a method of treating and/or preventing cancers presenting tumor-initiating cells. (Formula I) (I)
Inventors:
Virginie Clement-Chatro
Thomas facade
Riccardo Kriviu
Thomas facade
Riccardo Kriviu
Application Number:
JP2013540475A
Publication Date:
February 13, 2014
Filing Date:
November 24, 2011
Export Citation:
Assignee:
Stemage Biotechnology S.A.
International Classes:
C07C237/44; A01N37/46; A01N43/20; A01N43/24; A01N43/40; A01N43/42; A01N43/62; A01N43/72; A01N43/90; A01P3/00; A01P7/04; A01P13/00; A61K31/166; A61K31/22; A61K31/337; A61K31/357; A61K31/365; A61K31/366; A61K31/38; A61K31/39; A61K31/395; A61K31/397; A61K31/435; A61K31/44; A61K31/5025; A61K45/00; A61P31/04; A61P31/10; A61P35/00; C07D213/81; C07D221/04; C07D245/02; C07D267/00; C07D305/14; C07D321/00; C07D327/02; C07D407/06; C07D407/12; C07D409/12; C07D487/04; C07D491/107; C07D493/04; C07D493/10
Attorney, Agent or Firm:
Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda
Yoshihiro Nagare
Naoko Matsuda