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Title:
リポソームの中にカプセル化されたトリテルペノイド抗真菌薬の注射可能な組成物
Document Type and Number:
Japanese Patent JP7378401
Kind Code:
B2
Abstract:
Injectable compositions of single bilayer vesicles encapsulating enfumafungin derived triterpenoid antifungal compounds can be administered intravenously to treat or prevent fungal infections, while having reduced local injection site reactions (ISRs). The enfumafungin derived triterpenoid antifungal compounds are inhibitors of (1,3)-β-D-glucan synthesis and are useful in the treatment or prevention of fungal infections, such as systemic fungal infections, including those caused by Candida and Aspergillus species.

Inventors:
Motteramu, Rajeshwa
Application Number:
JP2020536766A
Publication Date:
November 13, 2023
Filing Date:
December 21, 2018
Export Citation:
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Assignee:
Cynexis, Inc.
International Classes:
A61K31/4439; A61K9/127; A61K47/24; A61K47/26; A61K47/28; A61P31/10
Domestic Patent References:
JP2011530593A
JP2007517909A
JP2014237729A
Attorney, Agent or Firm:
Makoto Ono
Kennori Kanayama
Yoshiyuki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yosuke Kawasaki
Takuya Gomibuchi
Youichi Iino
Yusuke Ichikawa
Masahiro Moriyama
Takashi Kawano
Yoshikazu Iwase
Yasufumi Shiroyama