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Title:
注入型ヒドロゲルシステムおよび病変の標識方法
Document Type and Number:
Japanese Patent JP7312822
Kind Code:
B2
Abstract:
The present invention provides an alginic acid-based injectable hydrogel system for labeling an accurate position of a disease lesion and effectively delivering a drug to a target region. The formulation of the present invention can make it easy to locally inject a contrast agent and a drug into a target region while controlling the release rate of the contrast agent or the drug, with the formation of the hydrogel in the injected region. Through the advantages, the labeled position can be accurately determined from images, thereby enhancing the precision of surgical operation, with a minimal incision formed therefor. In addition, when used, the alginic acid-based injectable hydrogel system allows the effective local delivery of a drug to a target region while increasing the long-acting effect of the drug.

Inventors:
Choi, Young Do
Lee, Son Souk
Kim, Hyun Jin
Song, Dae Kyung
Kim, Seok
Kim, Young Woo
Liu, Gun Won
Yun, Hong Man
Application Number:
JP2021523782A
Publication Date:
July 21, 2023
Filing Date:
November 01, 2019
Export Citation:
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Assignee:
National Cancer Center
International Classes:
A61K9/06; A61K47/02; A61K47/12; A61K47/18; A61K47/26; A61K47/36; A61K49/18; A61P23/00; A61P29/00; A61P35/00; A61P37/02
Domestic Patent References:
JP2001525826A
JP2001517494A
JP2001505809A
Foreign References:
KR1020060021967A
Attorney, Agent or Firm:
Hideki Miyata
Hiroaki Sakai