Title:
材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル
Document Type and Number:
Japanese Patent JP6567485
Kind Code:
B2
Abstract:
The invention provides compositions and methods to form pores in situ within hydrogels following hydrogel injection. Pores formed in situ via degradation of sacrificial porogens within the surround hydrogel facilitate recruitment or release of cells. Disclosed herein is a material that is not initially porous, but which becomes macroporous over time.
Inventors:
Hubish Nathaniel Dee.
Madel Christopher M.
Lee Kang Won
Shu Maria Em.
Mooney David Jay.
Madel Christopher M.
Lee Kang Won
Shu Maria Em.
Mooney David Jay.
Application Number:
JP2016203350A
Publication Date:
August 28, 2019
Filing Date:
October 17, 2016
Export Citation:
Assignee:
President and Fellows of Harvard College
International Classes:
A61L27/20; A61K9/06; A61K35/12; A61K35/15; A61K35/17; A61K35/28; A61K35/34; A61K35/44; A61K35/545; A61K38/18; A61K38/19; A61K38/22; A61K39/395; A61K47/30; A61K47/36; A61L27/14; A61L27/26; A61L27/38; A61L27/54
Domestic Patent References:
| JP2009519042A | ||||
| JP2007503881A |
Foreign References:
| WO2006136905A1 | ||||
| WO2010078209A1 |
Other References:
Biofabrication,2010年 9月,Vol.2, No.3,p.1-21
Biomaterials,2005年,Vol.26,p.2455-2465
Biomaterials,2005年,Vol.26,p.2455-2465
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Kazuya Kawamoto