Title:
一体型非対称膜、その製造方法およびその使用
Document Type and Number:
Japanese Patent JP5129962
Kind Code:
B2
Abstract:
A hydrophilic, semipermeable hollow-fibre membrane for blood treatment, with an integrally asymmetric structure based on a synthetic polymer. The hollow-fibre membrane possesses on its inner surface a porous separating layer and an open-pored supporting layer adjoining the separating layer, and has an ultrafiltration rate in albumin solution of 25 to 60 ml/(h.m2.mmHg). The hollow-fibre membrane is free from pore-stabilising additives, and has a minimum sieving coefficient for cytochrome c of 0.8 and maximum sieving coefficient for albumin of 0.005. Method for the preparation of such membranes based on coagulation induced by a non-solvent, whereby a spinning solution of a synthetic first polymer and possibly a hydrophilic second polymer is extruded into a hollow fibre through the annular slit of a hollow-fibre die with simultaneous extrusion of a coagulation medium as the interior filler through the central opening of the hollow-fibre die, the interior filler initiating coagulation in the interior of the hollow fibre as a result of which a separating layer on the inner surface of the hollow-fibre membrane is formed as well as the membrane structure, the method being characterised in that the interior filler contains a polyelectrolyte with negative fixed charges.
Inventors:
Fleet Belt Vex
Application Number:
JP2006553513A
Publication Date:
January 30, 2013
Filing Date:
February 15, 2005
Export Citation:
Assignee:
Membrana GmbH
International Classes:
B01D69/10; A61M1/16; A61M1/18; B01D61/24; B01D67/00; B01D69/02; B01D69/08; B01D69/12; B01D71/10; B01D71/44; B01D71/50; B01D71/64; B01D71/66; B01D71/68; D01D5/24; D01F2/00; D01F6/00; D01F6/76
Domestic Patent References:
| JP4176330A |
Attorney, Agent or Firm:
Toshio Yano
Takuya Kuno
Einzel Felix-Reinhard
Shuichi Sumiyoshi
Takuya Kuno
Einzel Felix-Reinhard
Shuichi Sumiyoshi