インテグリンαvβ6の阻害剤

Japanese Patent JP2004528325

A

Novel biphenyl derivatives of the general formula I in which R<1>, R<1'>, R<1''>, R<2 >and n are as defined in claim 1, their stereoisomers and their physiologically acceptable salts or solvates are novel integrin ligands, in particular of the alphavbeta6 integrin receptor. The novel compounds can be used as medicaments.

Shut, Oliver
Yonktsik, Alfrets
Stahl, Wolfgang
Guthman, Zimon

JP2002581384A

September 16, 2004

March 13, 2002

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A61K31/19; A61K31/197; A61K31/27; A61P1/16; A61P3/10; A61P3/14; A61P7/00; A61P7/02; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P13/00; A61P13/02; A61P13/12; A61P15/00; A61P15/08; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P19/10; A61P25/00; A61P27/00; A61P27/02; A61P27/06; A61P27/10; A61P29/00; A61P31/00; A61P31/04; A61P31/12; A61P31/18; A61P33/00; A61P35/00; A61P35/02; A61P37/04; A61P43/00; C07C269/06; C07C271/22; C07C273/18; C07C275/16; C07C275/18; A61P1/04; C07C275/20; C07C275/24; C07C275/26; C07C275/28; C07C275/30; C07C275/34; C07C275/42; C07C335/08; C07C335/12; C07K5/023; (IPC1-7): C07C271/22; A61K31/19; A61K31/197; A61K31/27; A61P1/04; A61P1/16; A61P3/10; A61P3/14; A61P7/02; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P13/02; A61P13/12; A61P15/00; A61P15/08; A61P17/00; A61P17/02; A61P17/06; A61P19/00; A61P19/02; A61P19/10; A61P25/00; A61P27/00; A61P27/02; A61P27/06; A61P27/10; A61P29/00; A61P31/04; A61P31/12; A61P31/18; A61P33/00; A61P35/00; A61P35/02; A61P37/04; A61P43/00; C07C269/06; C07C273/18; C07C275/16; C07C275/26; C07C275/42; C07C335/12

Akio Miyazaki
Nobuyuki Kaneda
Katsuhiro Ito
Ishibashi Masayuki

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