Title:
細孔を有する表面によって媒介される生体分子の細胞内送達
Document Type and Number:
Japanese Patent JP7046795
Kind Code:
B2
Abstract:
The present disclosure pertains to methods and devices for delivering a compound into a cell, including passing a cell suspension through a surface containing pores, wherein the pores deform the cell thereby causing a perturbation of the cell such that the compound enters the cell, wherein the cell suspension is contacted with the compound.
Inventors:
Gilbert, Jonathan Bee.
Flu, Kilbel
Bernstein, Howard
Charley, Armon Earl.
Flu, Kilbel
Bernstein, Howard
Charley, Armon Earl.
Application Number:
JP2018512328A
Publication Date:
April 04, 2022
Filing Date:
September 02, 2016
Export Citation:
Assignee:
Squeeze Biotechnology Company
International Classes:
C12N15/09; C12N5/07; C12N5/071; C12N5/0735; C12N5/074; C12N5/0775; C12N5/078; C12N5/0781; C12N5/0783; C12N5/0784; C12N5/0786; C12N5/0787; C12N5/0789; C12N5/079; C12N5/0793; C12N5/09; C12N5/10; C12N15/11; C12N15/113
Other References:
Biotechnol. Bioeng., 1999, Vol. 65, No. 3, pp. 341-346
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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