Title:
α-2アドレナリン受容体アゴニストの眼内インプラントおよび視力の向上方法
Document Type and Number:
Japanese Patent JP2007535552
Kind Code:
A
Abstract:
The present invention refers to a method of making a biodegradable intraocular implant, comprising the step of extruding a mixture of an alpha-2 adrenergic receptor agonist and a biodegradable polymer component to form a biodegradable material that releases drug at a rate effective to sustain release of an amount of the alpha-2 adrenergic receptor agonist from the implant for a time effective to reduce ocular vascular occlusion in an eye in which the implant is placed, the time being at least about one week after the implant is placed in the eye.
Inventors:
James Burke
Patrick M. Hughes
Jang Kai-Min
Tong Lin
Glen Ti Juan
Brittany a jackson
Larry A Wheeler
Rosie S. Don
Patrick M. Hughes
Jang Kai-Min
Tong Lin
Glen Ti Juan
Brittany a jackson
Larry A Wheeler
Rosie S. Don
Application Number:
JP2007510974A
Publication Date:
December 06, 2007
Filing Date:
April 26, 2005
Export Citation:
Assignee:
ALLERGAN,INCORPORATED
International Classes:
A61K9/06; A61K9/00; A61K31/498; A61K45/00; A61K47/36; A61K47/46; A61P27/02
Domestic Patent References:
| JP2004512378A | 2004-04-22 | |||
| JP2003527427A | 2003-09-16 | |||
| JPH02702A | 1990-01-05 | |||
| JPH1170138A | 1999-03-16 | |||
| JPH0517370A | 1993-01-26 | |||
| JPH06312943A | 1994-11-08 |
Foreign References:
| WO2003099795A1 | 2003-12-04 | |||
| WO2003077952A1 | 2003-09-25 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Kyousei Tamura
Yasuo Shibata
Kenichi Morizumi
Nagatoshi Shinagawa
Takuji Yamada
Kyousei Tamura
Yasuo Shibata
Kenichi Morizumi
Nagatoshi Shinagawa