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Title:
IONENE POLYMER AS ANTIMICROBIAL AGENT AND APPLICATION OF THE SAME
Document Type and Number:
Japanese Patent JP2007162024
Kind Code:
A
Abstract:

To provide a safe and nontoxic antimicrobial agent having durability for a long period of time and developing minimum generation of resistant or multiply resistant microbes.

The ionene polymer having antimicrobial activity is a cationic polymer in which a substantial proportion of the atoms providing the positive charge are quaternized nitrogen atoms located in the main polymeric chain or backbone of the polymer rather than in pendant groups. The method includes the ionene polymer-containing antimicrobial composition and administration of a therapeutically effective amount of the antimicrobial composition to a mammal for treating persistent microbial infection. Also the method includes the ionene polymer-containing antimicrobial composition and a process for bringing a susceptible surface into contact with the composition to prevent, inhibit or exclude growth, dissemination and/or accumulation of microorganisms on the susceptible surface (including, but not limited to, the spasticity of biofilms on the susceptible surface).


Inventors:
FITZPATRICK RICHARD
KLINGER JEFFREY D
SHACKETT KEITH K
Application Number:
JP2006333694A
Publication Date:
June 28, 2007
Filing Date:
December 11, 2006
Export Citation:
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Assignee:
GENZYME CORP
International Classes:
C08G73/00; A01N25/10; A01N33/12; A01N47/44; A01N57/34; A61K31/74; A61K31/785; A61K31/787; A61K31/80; A61P1/00; A61P1/02; A61P17/00; A61P31/00; A61P31/02; A61P31/04; A61P31/10; A61P31/12; A61P33/00; C08G61/12; C08G73/02; C08G73/06; C08G79/06
Domestic Patent References:
JPH032219A1991-01-08
JPH02116843A1990-05-01
JP2001527458A2001-12-25
JPH0892017A1996-04-09
JPH07318526A1995-12-08
Foreign References:
US4499077A1985-02-12
US4891423A1990-01-02
US2643232A1953-06-23
WO2000035861A12000-06-22
Attorney, Agent or Firm:
Yoshinori Hosoda