Title:
Iso oxazolo quinazoline as an adjustment agent of protein kinase activity
Document Type and Number:
Japanese Patent JP5997143
Kind Code:
B2
Abstract:
The present invention relates to substituted isoxazolo-quinazolines which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular human MPS1 and PERK. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.
Inventors:
Caldereturi, Marina
Berea, Italo
Colombo, Nicoletta
Piutstay, Claudia
Salsa, Matsuteo
Gabriel Zla
Berea, Italo
Colombo, Nicoletta
Piutstay, Claudia
Salsa, Matsuteo
Gabriel Zla
Application Number:
JP2013521070A
Publication Date:
September 28, 2016
Filing Date:
July 20, 2011
Export Citation:
Assignee:
Nerbiano Medieval Sciences Etse Erle Erle
International Classes:
C07D498/04; A61K31/519; A61P35/00; A61P43/00
Domestic Patent References:
| JP2010513389A | ||||
| JP2007502851A | ||||
| JP2005526730A |
Foreign References:
| WO2009156315A1 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office
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