Title:
カルバミン酸誘導体および代謝型グルタミン酸受容体配位子としてその使用
Document Type and Number:
Japanese Patent JP3751825
Kind Code:
B2
Abstract:
The present invention is a compound of formula:wherein R1, R2, R2', X, A1/A2 and B are as defined in the specification.These compounds may be used in the control or prevention of acute and/or chronic neurological disorders such as restricted brain function caused by bypass operations or transplants, poor blood supply to the brain, spinal cord injuries, head injuries, hypoxia caused by pregnancy, cardiac arrest, hypoglycaemia, Alzheimer's disease, Huntington's chorea, ALS, dementia caused by AIDS, eye injuries, retinopathy, cognitive disorders, memory deficits, schizophrenia, idiopathic parkinsonism or parkinsonism caused by medicaments as well as conditions which lead to glutamate deficiency functions, such as e.g. muscle spasms, convulsions, migraine, urinary incontinence, nicotine addiction, psychoses, opiate addiction, anxiety, vomiting, acute and chronic pain, dyskinesia and depression.
Inventors:
Breicher, Konrad
Muntel, Vincent
Eric, Fieira
Wichmann, Jurgen
Volterring, Thomas Johannes
Muntel, Vincent
Eric, Fieira
Wichmann, Jurgen
Volterring, Thomas Johannes
Application Number:
JP2000612262A
Publication Date:
March 01, 2006
Filing Date:
April 19, 2000
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07C271/64; A61K31/325; C07D295/08; A61K31/352; A61K31/381; A61K31/382; A61K31/421; A61K31/422; A61K31/4245; A61K31/4409; A61K31/5375; A61P25/00; A61P25/06; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/34; A61P27/02; C07C233/90; C07C233/91; C07C333/10; C07D213/30; C07D213/60; C07D213/61; C07D263/48; C07D271/07; C07D271/10; C07D271/113; C07D295/088; C07D311/84; C07D333/16; C07D335/12; C07D335/14; C07D409/12; C07D413/12; C07D213/00; C07D271/00; C07D271/06
Domestic Patent References:
| JP10182629A | ||||
| JP3912921B1 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda