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Title:
合成HCV外被蛋白質及びワクチンのためのその使用
Document Type and Number:
Japanese Patent JP2005510211
Kind Code:
A
Abstract:
The present invention relates to the amino acid and deduced nucleic acid sequence of synthetic E2 proteins comprising a consensus sequence of the most conserved amino acids found in E2 of 77 different HCV 1b isolates worldwide. The invention further relates to a truncated version of the E2 protein lacking HVR1. Another aspect of the present invention concerns a vaccine comprising the E2 proteins.

Inventors:
Neville, Lewis
Sauberman, Ally
Application Number:
JP2003526952A
Publication Date:
April 21, 2005
Filing Date:
September 09, 2002
Export Citation:
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Assignee:
X-Stay by Offer Mousticals Limited
International Classes:
C12N15/09; A61K35/76; A61K38/00; A61K39/00; A61K48/00; A61P31/14; C07K14/18; C07K16/10; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/40; C12N15/51; G01N33/576; (IPC1-7): C12N15/09; A61K35/76; A61K38/00; A61K39/00; A61K48/00; A61P31/14; C07K14/18; C07K16/10; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Naganuma Akio
Yukihiro Ikeda