Title:
ＫＣＮＱ２〜５チャネル活性化剤
Document Type and Number:
Japanese Patent JP6943239
Kind Code:
B2
Abstract:
An object of the present invention is to provide a novel compound having a strong opening action with respect to KCNQ2-5 channels. A compound represented by the general formula (I) (wherein the definition of each group is as described in the specification) is provided. The compound represented by the general formula (I) has a strong opening action with respect to KCNQ2-5 channels, and therefore is useful as a prophylactic and/or therapeutic agent for a KCNQ2-5 channel-related disease (for example, dysuria, overactive bladder, or the like).
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Inventors:
Kentaro Yatsushiro
Hitoshi Kato
Tetsuji Saito
Takuya Okada
Wakamatsu
Davenport, Adam James
Stimson, Christopher Charles
Hitoshi Kato
Tetsuji Saito
Takuya Okada
Wakamatsu
Davenport, Adam James
Stimson, Christopher Charles
Application Number:
JP2018513233A
Publication Date:
September 29, 2021
Filing Date:
April 21, 2017
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
C07C271/30; A61K31/17; A61K31/341; A61K31/351; A61K31/4045; A61K31/42; A61K31/44; A61K31/4545; A61P13/02; A61P13/10; A61P43/00; C07C275/32; C07D209/14; C07D213/40; C07D213/64; C07D213/74; C07D261/08; C07D277/28; C07D307/52; C07D309/04; C07F15/00
Domestic Patent References:
| JP2010511052A |
Foreign References:
| CN104327083A | ||||
| WO2016063990A3 |
Other References:
RN 1026819-61-3 2008.06.09 Registry [online],American Chemical Society,[retrieved on 2017.07.05], Retrieved from: STN
Attorney, Agent or Firm:
Atsushi Aoki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takahide Sasaki
Shinji Mitsuhashi
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takahide Sasaki