Title:
疾患の治療のためのＫＤＭ１Ａ阻害剤
Document Type and Number:
Japanese Patent JP6727216
Kind Code:
B2
Abstract:
Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.
Inventors:
Leanhof Hugh, Young, Junior
McCall John M.
Claire Michael
Ceratoka Cassandra
Tupper Amy, E.
McCall John M.
Claire Michael
Ceratoka Cassandra
Tupper Amy, E.
Application Number:
JP2017536938A
Publication Date:
July 22, 2020
Filing Date:
February 12, 2016
Export Citation:
Assignee:
Imago Biosciences, Inc.
International Classes:
A61K31/397; C07D249/06; A61K31/4155; A61K31/4162; A61K31/4178; A61K31/4192; A61K31/4196; A61K31/438; A61K31/445; A61K31/454; A61K31/495; A61K31/496; A61K31/4995; A61K31/501; A61K31/506; A61K31/5355; A61K31/5386; A61K31/54; A61K31/541; A61K31/551; A61K45/00; A61P1/04; A61P7/00; A61P7/02; A61P7/06; A61P19/02; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07D205/04; C07D207/327; C07D211/58; C07D211/66; C07D213/84; C07D215/54; C07D231/12; C07D231/14; C07D237/08; C07D239/26; C07D239/42; C07D241/12; C07D249/08; C07D257/04; C07D263/32; C07D295/185; C07D295/26; C07D401/12; C07D403/12; C07D413/12; C07D471/10; C07D487/04; C07D487/08; C07D491/107
Domestic Patent References:
| JP2013540767A |
Foreign References:
| WO2014164867A1 | ||||
| WO2014084298A1 |
Attorney, Agent or Firm:
Masahiro Nanjo
Ayako Seta
Koichiro Inami
Hidetoshi Hara
Ayako Seta
Koichiro Inami
Hidetoshi Hara