Title:
A Kajanin similar structure compound, a preparing method, and a use
Document Type and Number:
Japanese Patent JP6203746
Kind Code:
B2
Abstract:
Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.
Inventors:
Lee Duolon
The Shin-yao
Shoe Stu
Zheng Gwang-hui
Lee Yu Hoang
Tao Payzen
Gian Jeandon
The Shin-yao
Shoe Stu
Zheng Gwang-hui
Lee Yu Hoang
Tao Payzen
Gian Jeandon
Application Number:
JP2014547669A
Publication Date:
September 27, 2017
Filing Date:
December 18, 2012
Export Citation:
Assignee:
Institute of Medicine and Biotechnology, Chinese Academy of Medical Sciences
International Classes:
C07C39/21; A61K31/05; A61K31/085; A61K31/09; A61K31/155; A61K31/166; A61K31/17; A61K31/192; A61K31/216; A61K31/223; A61K31/225; A61K31/27; A61K31/353; A61K31/381; A61K31/401; A61K31/4164; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4468; A61K31/495; A61P3/00; A61P3/06; A61P3/10; A61P19/10; A61P25/00; A61P31/00; A61P31/12; C07C39/215; C07C43/215; C07C43/23; C07C65/28; C07C69/157; C07C69/36; C07C69/92; C07C69/94; C07C217/20; C07C217/22; C07C229/08; C07C229/12; C07C235/46; C07C235/62; C07C235/64; C07C275/54; C07C275/70; C07C279/22; C07C281/02; C07D207/16; C07D211/58; C07D213/55; C07D213/64; C07D213/65; C07D213/68; C07D213/69; C07D213/80; C07D233/60; C07D233/90; C07D241/04; C07D333/16; C07D333/24
Foreign References:
| CN102276433A | ||||
| CN101569654A | ||||
| US6552085 | ||||
| US6541522 |
Other References:
European Journal of Organic Chemistry,2010年,Vol.2010, No.2,p.333-337
Organic Letters,2010年,Vol.12, No.6,p.1364-1367
Phytochemistry,1971年,Vol.10, No.11,p.2837-2838
Lloydia,1977年,Vol.40, No.2,p.201-208
Organic Letters,2010年,Vol.12, No.6,p.1364-1367
Phytochemistry,1971年,Vol.10, No.11,p.2837-2838
Lloydia,1977年,Vol.40, No.2,p.201-208
Attorney, Agent or Firm:
Patent Business Corporation Ark Patent Office