Title:
コレステロールの制御及び関連する使用のためのケトン化合物及び組成物
Document Type and Number:
Japanese Patent JP2004511453
Kind Code:
A
Abstract:
The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising a ketone compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
Inventors:
Dashu, Jean-Lewis, H.
Onishiu, Carmen, Daniela
Onishiu, Carmen, Daniela
Application Number:
JP2002534250A
Publication Date:
April 15, 2004
Filing Date:
October 11, 2001
Export Citation:
Assignee:
Esperion Therapeutics, Incorporated
International Classes:
A23K1/16; A61K31/10; A61K31/121; A61K31/16; A61K31/194; A61K31/20; A61K31/225; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P7/02; A61P9/00; A61P9/12; A61P13/12; A61P15/10; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P43/00; C07C49/17; C07C49/185; C07C49/215; C07C49/245; C07C49/258; C07C49/507; C07C49/723; A23K1/18; C07C49/743; C07C49/747; C07C49/782; C07C49/82; C07C49/83; C07C49/86; C07C50/30; C07C59/347; C07C59/353; C07C59/84; C07C69/716; C07C69/738; C07C235/74; C07C261/04; C07C309/07; C07C309/24; C07D233/72; C07D233/84; C07D233/86; C07D257/04; C07D261/12; C07D305/12; C07D307/33; C07D309/12; C07D309/30; C07D309/40; C07D495/04; C07F9/09; C07F9/24; C07F9/44; (IPC1-7): C07C49/17; A23K1/16; A23K1/18; A61K31/10; A61K31/121; A61K31/16; A61K31/194; A61K31/20; A61K31/225; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P7/02; A61P9/00; A61P9/12; A61P13/12; A61P15/10; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P43/00; C07C49/245; C07C49/83; C07C59/84; C07C69/716; C07C235/74
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Ishii Teiji
Satoshi Fujita
Ishii Teiji