Title:
ジアゾメチル官能基を持つピリジン核を有する標識化試薬、該試薬の合成方法および生体分子の検出方法
Document Type and Number:
Japanese Patent JP5465724
Kind Code:
B2
Abstract:
A process for synthesis of a labelling reagent, a process for the labelling of a biological molecule, a labelled biological molecule obtained by the process, a process for labelling and fragmentation of a single or double strand nucleic acid, a labelled nucleic acid capable of being obtained by the process, a kit for detection of a target nucleic acid containing a labelled nucleic acid, a solid support onto which is attached a reagent and a process for capture of nucleic acids.
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Inventors:
Laurent, Alan
Rayoun, Ali
Kotera Koji
Rayoun, Ali
Kotera Koji
Application Number:
JP2011520567A
Publication Date:
April 09, 2014
Filing Date:
July 28, 2009
Export Citation:
Assignee:
BIOMERIEUX
Universite de Strasbourg
Universite de Strasbourg
International Classes:
C12N15/09; C07D213/24; C07D233/32; C07D333/24; C12Q1/68; G01N21/78; G01N33/50; G01N33/58
Foreign References:
| WO2009001017A2 | ||||
| WO2005092910A1 | ||||
| WO2002090584A2 |
Other References:
SHIGA M,FLUORESCENCE DETECTION OF DNA USING A NOVEL PEROXIDASE SUBSTRATE, 以下備考,ANALYTICAL SCIENCES,JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY,1995年 8月 1日,V11 N4,P591-595,4-(4-HYDROXYPHENYLCARBAMOYL)BUTANOIC ACID
LAAYOUN A,ARYLDIAZOMETHANES FOR UNIVERSAL LABELING OF NUCLEIC ACIDS AND ANALYSIS ON DNA CHIPS,BIOCONJUGATE CHEMISTRY,ACS,2003年 1月 1日,V14 N1,P1298-1306
SHIGA M,SYNTHESIS OF A NOVEL BIOTIN DERIVATIVE THAT BEARS A DIAZO GROUP AS THE REACTIVE SITE,ANALYTICAL SCIENCES,JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY,1993年 8月 1日,V9 N4,P553-556
LAAYOUN A,ARYLDIAZOMETHANES FOR UNIVERSAL LABELING OF NUCLEIC ACIDS AND ANALYSIS ON DNA CHIPS,BIOCONJUGATE CHEMISTRY,ACS,2003年 1月 1日,V14 N1,P1298-1306
SHIGA M,SYNTHESIS OF A NOVEL BIOTIN DERIVATIVE THAT BEARS A DIAZO GROUP AS THE REACTIVE SITE,ANALYTICAL SCIENCES,JAPAN SOCIETY FOR ANALYTICAL CHEMISTRY,1993年 8月 1日,V9 N4,P553-556
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori