Title:
LENTIVIRAL VECTOR-BASED IMMUNOLOGICAL COMPOUNDS AGAINST MALARIA
Document Type and Number:
Japanese Patent JP2016041076
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide immunological compounds against malaria based on lentiviral vectors.SOLUTION: The invention relates to a lentiviral vector particle (i) which is pseudotyped with at least one determined heterologous viral envelope protein originating from a RNA virus and (ii) which comprises in its genome at least one recombinant polynucleotide encoding at least one polypeptide comprising at least one epitope of a pre-erythrocytic stage antigen of a Plasmodium parasite capable of infecting a mammalian host, where the epitope(s) comprises T-epitope(s) and optionally B-epitope(s).SELECTED DRAWING: None
Inventors:
CHARNEAU PIERRE
FREDERIC PHILIPPE COUTANT
FREDERIC PHILIPPE COUTANT
Application Number:
JP2015233691A
Publication Date:
March 31, 2016
Filing Date:
November 30, 2015
Export Citation:
Assignee:
PASTEUR INSTITUT
THERAVECTYS
THERAVECTYS
International Classes:
C12N7/04; A61K35/76; A61K39/015; A61K48/00; A61P33/06; A61P37/04; A61K39/00
Foreign References:
| WO2007095201A2 | 2007-08-23 | |||
| WO2009019612A2 | 2009-02-12 | |||
| WO2004043488A1 | 2004-05-27 |
Other References:
K. J. LIMBACH AND T. L. RICHIE, PARASITE IMMUNOLOGY, vol. Vol. 31, No. 9, JPN6014041070, 10 June 2009 (2009-06-10), pages PP. 501-519
JOHN A. TINE, ET AL., INFECTION AND IMMUNITY, vol. Vol. 64, No. 9, JPN6014041071, 1 September 1996 (1996-09-01), pages PP. 3833-3844
CARLOTA DOBANO, ET AL., EXPERIMENTAL PARASITOLOGY, vol. Vol. 122, Issue. 2, JPN6014041061, 26 February 2009 (2009-02-26), pages PP. 112-123
OSCAR BRUNA-ROMERO, ET AL., VACCINE, vol. Vol. 22, Issue. 27-28, JPN6014041063, 27 April 2004 (2004-04-27), pages PP. 3575-3584
C. SPEAKE AND P. E. DUFFY, PARASITE IMMUNOLOGY, vol. Vol. 31, Issue. 9, JPN6014041073, 12 June 2009 (2009-06-12), pages PP. 539-546
C. DOBANO AND D. L. DOOLAN, MOLECULAR IMMUNOLOGY, vol. Vol. 44, Issue. 11, JPN6014041076, 15 February 2007 (2007-02-15), pages PP. 3037-3048
FREDERIC COUTANT, ET AL., PLOS ONE, vol. Vol. 3, No. 12, JPN6014041065, 19 December 2008 (2008-12-19), pages PP. E3973
ANNE-SOPHIE BEIGNON, ET AL., JOURNAL OF VIROLOGY, vol. Vol. 83, No. 21, JPN6014041068, 12 August 2009 (2009-08-12), pages PP. 10963-10974
JOHN A. TINE, ET AL., INFECTION AND IMMUNITY, vol. Vol. 64, No. 9, JPN6014041071, 1 September 1996 (1996-09-01), pages PP. 3833-3844
CARLOTA DOBANO, ET AL., EXPERIMENTAL PARASITOLOGY, vol. Vol. 122, Issue. 2, JPN6014041061, 26 February 2009 (2009-02-26), pages PP. 112-123
OSCAR BRUNA-ROMERO, ET AL., VACCINE, vol. Vol. 22, Issue. 27-28, JPN6014041063, 27 April 2004 (2004-04-27), pages PP. 3575-3584
C. SPEAKE AND P. E. DUFFY, PARASITE IMMUNOLOGY, vol. Vol. 31, Issue. 9, JPN6014041073, 12 June 2009 (2009-06-12), pages PP. 539-546
C. DOBANO AND D. L. DOOLAN, MOLECULAR IMMUNOLOGY, vol. Vol. 44, Issue. 11, JPN6014041076, 15 February 2007 (2007-02-15), pages PP. 3037-3048
FREDERIC COUTANT, ET AL., PLOS ONE, vol. Vol. 3, No. 12, JPN6014041065, 19 December 2008 (2008-12-19), pages PP. E3973
ANNE-SOPHIE BEIGNON, ET AL., JOURNAL OF VIROLOGY, vol. Vol. 83, No. 21, JPN6014041068, 12 August 2009 (2009-08-12), pages PP. 10963-10974
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Takahide Sasaki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Takahide Sasaki