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Title:
【発明の名称】脂質誘導体
Document Type and Number:
Japanese Patent JPH0745454
Kind Code:
B2
Abstract:
Novel lipid derivatives of the formula [wherein R<1> is alkyl or alkylcarbamoyl; R<2> is hydrogen, hydroxy which may be substituted, amino which may be substituted or cyclic amino; R<3> is chemical binding or alkylene which may be substituted; R<4> is hydrogen, alkyl or aralkyl; X and Y are independently O, S or an imino group which may be substituted, and when Y is an imino group, Y, together with the imino group represented by X or R<4>, may form a ring; and Z is imino or a nitrogen-containing heterocyclic ring which may be substituted] and salts thereof have inhibiting activity on platelet activating factor and are useful as a preventive or therapeutic agent for a variety of circulatory diseases and allergic disorders and also as an antineoplastic agent.

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Inventors:
Nomura Yoro
Kohei Nishikawa
Tsushima Susumu
Application Number:
JP6962885A
Publication Date:
May 17, 1995
Filing Date:
April 01, 1985
Export Citation:
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Assignee:
Takeda GmbH
International Classes:
A61K31/265; A61K31/23; A61K31/27; A61K31/40; A61K31/415; A61K31/4166; A61K31/425; A61K31/426; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4418; A61K31/4425; A61K31/445; A61K31/455; A61K31/495; A61K31/535; A61P7/02; A61P9/12; A61P29/00; A61P37/08; A61P43/00; C07C67/00; C07C219/16; C07C239/00; C07C239/20; C07C269/00; C07C271/06; C07C275/50; C07C275/60; C07C325/00; C07C329/06; C07C333/04; C07C333/16; C07D207/09; C07D209/48; C07D211/56; C07D213/40; C07D213/75; C07D213/80; C07D233/72; C07D239/54; C07D277/20; C07D277/22; C07D277/28; C07D295/088; C07D295/12; C07D295/13; C07D295/205; C07D295/215; C07D401/06; C07D401/12; C07D405/12; C07D417/06; C07D417/12; C07D521/00; (IPC1-7): C07C239/20; C07C333/04; C07D207/09; C07D211/56; C07D233/72; C07D277/20; C07D293/00; C07D333/04; C07D401/06; C07D401/12; C07D403/12; C07D405/12; C07D417/06; C07D417/12
Attorney, Agent or Firm:
Hiroshi Iwata



 
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