Title:
トランスフェクション剤としてのリポポリアミン及びその医薬的使用
Document Type and Number:
Japanese Patent JP4176831
Kind Code:
B2
Abstract:
Lipopolyamines useful for the transfection of nucleic acid and methods of preparation thereof are disclosed. The lipopolyamines are of general formula I, in which R4 comprises at least one C10-C22 aliphatic radical.
Inventors:
Bituk, the gerard
Daniel Cielman
Shwaltz, Bertrand
Doubertre, Catherine
Daniel Cielman
Shwaltz, Bertrand
Doubertre, Catherine
Application Number:
JP51862197A
Publication Date:
November 05, 2008
Filing Date:
November 08, 1996
Export Citation:
Assignee:
Avantes Furuma S.A.
International Classes:
A61K48/00; A61K31/70; C12N15/09; A61K31/7088; A61K47/34; A61K47/48; A61P35/00; A61P43/00; C07C237/06; C07C237/12; C07D495/04; C07H15/12; C07J41/00; C07K5/02; C07K5/06; C07K7/02; C12N15/87; C12N15/88; G11B5/012; G11B5/02; G11B5/09; G11B19/04; G11B20/18; G11B20/24; A61K38/00; G11B5/00; G11B20/10; G11B20/12
Domestic Patent References:
| JP4270257A | ||||
| JP11510489A |
Foreign References:
| DE1165038A1 |
Other References:
Benz, H. et al, Synthesis of analogs of polyamine spider toxins, Helvetica Chimica Acta, スイス, 1994年, 77(4), p.957-971
Attorney, Agent or Firm:
Yoshio Kawaguchi