リポソーム組成物および医薬組成物

Title:

リポソーム組成物および医薬組成物

Document Type and Number:

Japanese Patent JP7012124

Kind Code:

B2

Abstract:

An object of the present invention is to provide a liposome composition and a pharmaceutical composition, which exhibit a high AUC. Provided are a liposome composition including a hydrophilic polymer-modified diacylphosphatidylethanolamine, a dihydrosphingomyelin, and cholesterols as components of a liposome membrane, in which the liposome composition encapsulates a drug, an inner water phase thereof contains ammonium sulfate, and a molar ratio of sulfate ions in the inner water phase to the drug in an entire water phase is 0.36 or more; and a pharmaceutical composition including the liposome composition.

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Inventors:

Noriyuki Kasagi
Naoki Yamada
Mori Nagano
Takayuki Kato
Takayuki Kobayashi

Application Number:

JP2020113828A

Publication Date:

January 27, 2022

Filing Date:

July 01, 2020

Export Citation:

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Assignee:

FUJIFILM Corporation

International Classes:

A61K9/127; A61K31/404; A61K31/4745; A61K31/704; A61K47/14; A61K47/18; A61K47/20; A61K47/24; A61K47/28; A61P35/00; H01M50/204; H01M50/296; H01M50/591

Domestic Patent References:

JP2016117005A
JP2008519045A

Attorney, Agent or Firm:

Patent Service Corporation Patent Office Sykes

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