Title:
リポキシンA4類似体
Document Type and Number:
Japanese Patent JP4510919
Kind Code:
B2
Abstract:
This invention is directed to compounds useful as intermediates in the synthesis of lipoxin A4 analogs of the following formulas (I) and (II): wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.
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Inventors:
Bauman, John Gee.
Guildford, William Jay.
Parkinson, John F.
Sukhbara, Berner
Sabra Maniab, Bab
Guildford, William Jay.
Parkinson, John F.
Sukhbara, Berner
Sabra Maniab, Bab
Application Number:
JP2009142783A
Publication Date:
July 28, 2010
Filing Date:
June 15, 2009
Export Citation:
Assignee:
Bayer Schering Pharma Aktiengesellschaft
International Classes:
C07C59/68; C07D317/40; A61K31/16; A61K31/165; A61K31/19; A61K31/202; A61K31/216; A61K31/357; A61K31/39; A61K31/42; A61P1/02; A61P1/04; A61P3/10; A61P7/04; A61P9/10; A61P9/12; A61P11/00; A61P13/08; A61P13/12; A61P17/00; A61P17/06; A61P19/02; A61P25/00; A61P25/06; A61P25/16; A61P25/28; A61P27/02; A61P27/06; A61P27/16; A61P29/00; A61P31/00; A61P31/04; A61P31/18; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07C59/135; C07C59/70; C07C69/708; C07C69/734; C07C69/736; C07C209/68; C07C217/46; C07C229/12; C07C235/06; C07C235/34; C07C323/52; C07D263/24; C07D317/22; C07D317/72; C07D327/04
Domestic Patent References:
| JP8512023A | ||||
| JP2002539159A |
Foreign References:
| WO2000055109A1 | ||||
| WO1995001179A1 |
Other References:
Takano, T. et al.,Journal of Clinical Investigation,1998年 2月15日,Vol.101, No.4,p.819-826
Serhan, C. et al.,Advances in Experimental Medicine and Biology,1999年,Vol.469,p.287-293
Jane F.Maddox, et al.,Journal of Biological Chemistry,1997年,Vol.272, No.11,p.6972-6978
Serhan, C. et al.,,Biochemistry,1995年,Vol.34,p.14609-14615
Serhan, C. et al.,Advances in Experimental Medicine and Biology,1999年,Vol.469,p.287-293
Jane F.Maddox, et al.,Journal of Biological Chemistry,1997年,Vol.272, No.11,p.6972-6978
Serhan, C. et al.,,Biochemistry,1995年,Vol.34,p.14609-14615
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Masaru Nakajima