Title:
肝癌の検出方法及び肝癌診断薬並びに癌治療薬
Document Type and Number:
Japanese Patent JP4695982
Kind Code:
B2
Abstract:
Disclosed are a method for detecting liver cancer capable of detecting liver cancer with high specificity and a diagnostic therefor, as well as a novel therapeutic drug for cancer having an excellent anticancer effect. The method for detecting liver cancer cells in a sample utilizes as an index the expression of dlk gene. The expression of dlk gene may be measured by immunoassay using an anti-dlk antibody or by measuring mRNA of dlk gene. The therapeutic drug for cancer comprises as an effective ingredient an antibody which undergoes antigen-antibody reaction with Dlk expressing on surfaces of cancer cells and which exerts anticancer action against the cancer cells.
Inventors:
Koji Nakamura
Hiroko Anzai
Hiroyuki Yanagiuchi
Atsushi Miyajima
Hiroko Anzai
Hiroyuki Yanagiuchi
Atsushi Miyajima
Application Number:
JP2005515795A
Publication Date:
June 08, 2011
Filing Date:
November 25, 2004
Export Citation:
Assignee:
Kanagawa Academy of Science and Technology
International Classes:
A61K39/395; A61P35/00; C07K16/30; C12Q1/68; G01N33/574; C12N15/09
Domestic Patent References:
| JPH08509358A | 1996-10-08 |
Foreign References:
| WO2004030615A2 | 2004-04-15 | |||
| WO2002081625A2 | 2002-10-17 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Koichi Iwata
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Koichi Iwata
Yasuhito Suzuki