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Title:
低置換度ヒドロキシプロピルセルロース及び固形製剤
Document Type and Number:
Japanese Patent JP7145128
Kind Code:
B2
Abstract:
There is provided low-substituted hydroxypropyl cellulose (L-HPC) having good bindability, anti-capping performance and disintegratability. More specifically, there are provided L-HPC having a hydroxypropoxy group content of 5 to 16% by mass and a volume fraction of long fibrous particles of more than 50.0% relative to all of L-HPC particles which are classified, on a basis of dynamic image analysis, into fine particles, spherical particles, the long fibrous particles and short fibrous particles; and a solid preparation containing the L-HPC.

Inventors:
Tsubasa Oguro
Yasuyuki Hirama
Application Number:
JP2019149384A
Publication Date:
September 30, 2022
Filing Date:
August 16, 2019
Export Citation:
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Assignee:
Shin-Etsu Chemical Co., Ltd.
International Classes:
C08B11/08; A61K47/38
Domestic Patent References:
JP2018062654A
JP2003238448A
Foreign References:
US6380381
Attorney, Agent or Firm:
Mitsuo Matsui
Hiroshi Murakami
Yukari Kato
Kawamura English