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Title:
LOXOPROFEN-CONTAINING EXTERNAL PREPARATION
Document Type and Number:
Japanese Patent JP2012214444
Kind Code:
A
Abstract:

To prevent occurrence of deposition/precipitation when pH of an external preparation containing loxoprofen is lowered by an acid and/or an acidic substance.

Occurrence of deposition/precipitation can be prevented by combining specific surfactants, in details, polyoxyethylene hydrogenated castor oil 40, polyoxyethylene hydrogenated castor oil 50, and polyoxyethylene hydrogenated castor oil 60.


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Inventors:
MARUMOTO AYA
SUZUKI KAZUHIRO
KOHIDA HIDEKI
Application Number:
JP2012059521A
Publication Date:
November 08, 2012
Filing Date:
March 16, 2012
Export Citation:
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Assignee:
TAISHO PHARMACEUTICAL CO LTD
International Classes:
A61K31/192; A61K9/107; A61K47/02; A61K47/12; A61K47/34; A61P1/02; A61P17/02; A61P19/02; A61P29/00
Domestic Patent References:
JPS62181226A1987-08-08
JPH0741422A1995-02-10
JP2001199883A2001-07-24
JP2002128703A2002-05-09
JP2011051980A2011-03-17
JP2003212772A2003-07-30
JPH06247853A1994-09-06
JPH05186343A1993-07-27
JP2002080365A2002-03-19
Foreign References:
WO2006048939A12006-05-11



 
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