Title:
ＭＥＬＫエピトープペプチドおよびそれを含むワクチン
Document Type and Number:
Japanese Patent JP5816918
Kind Code:
B2
Abstract:
According to the present invention, peptides having the amino acid sequence of SEQ ID NOs: 14, 21, 23, 27, 36, 46, 57, 60 and 62 were demonstrated to have cytotoxic T lymphocyte (CTL) inducibility. Therefore, the present invention provides a peptide having the amino acid sequence selected from among SEQ ID NOs: 14, 21, 23, 27, 36, 46, 57, 60 and 62. The peptide can include one, two, or several amino acid substitutions, deletions, insertions, or additions so long as its CTL inducibility is retained. Furthermore, the present invention provides pharmaceutical agents for the treatment and/or prophylaxis of cancers, and/or prevention of postoperative recurrence thereof, which contain any of these peptides. Pharmaceutical agents of this invention include vaccines.
Inventors:
Takuya Tsunoda
Ryuji Osawa
Ryuji Osawa
Application Number:
JP2011504270A
Publication Date:
November 18, 2015
Filing Date:
July 30, 2009
Export Citation:
Assignee:
OncoTherapy Science Co., Ltd.
International Classes:
C07K7/06; C12N15/09; A61K31/7088; A61K38/00; A61K38/08; A61K39/00; A61P35/00; C12N5/0783; C12N5/0784; C12N5/0786; C12N5/10; C12N15/11
Foreign References:
| WO2005073374A1 | ||||
| WO2006091734A1 | ||||
| WO2007032255A1 |
Other References:
99th AACR Annual Meeting,2008年 4月,Abstract #4631,URL,http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/4631?maxtoshow=&hits=10&RESULTFORMAT=&author1=Tetsuro+Sasada&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto