Title:
MR diagnostic imaging for intractable neurological diseases
Document Type and Number:
Japanese Patent JP6367120
Kind Code:
B2
Abstract:
Disclosed is a compound represented by formula (1) or a salt thereof, formula (1) :
wherein X is a residue of a compound having activity of binding to at least one member selected from the group consisting of amyloid ² proteins, tau proteins, ±-synuclein, and TDP-43; m is an integer of 0 to 6; n is an integer of 1 to 5; and J is a group selected from the group consisting of
wherein R 1 and R 2 are each independently a hydrogen atom, a fluorine atom, methyl, or trifluoromethyl; R 3 is trifluoromethyl or trifluoromethoxy; and p is an integer of 1 to 4, provided that m + n ¥ 5 when J is J-1, and m + n ¥ 7 when J is J-2 or J-3.
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Inventors:
Toyama Ikuo
Hiroyasu Taguchi
Daijiro Yanagisawa
Hiroyasu Taguchi
Daijiro Yanagisawa
Application Number:
JP2014556404A
Publication Date:
August 01, 2018
Filing Date:
January 06, 2014
Export Citation:
Assignee:
Shiga University of Medical Science
International Classes:
C07D263/56; A61B5/055; A61K49/06; C07C69/738; C07C235/34; G01N24/00
Domestic Patent References:
| JP2009067762A | ||||
| JP2008546804A |
Foreign References:
| WO2007111179A1 | ||||
| WO2010098502A1 |
Other References:
Neuroscience Research,2009年,Vol.63, No.1,P.76-81
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office